Transcribing RNA polymerase III observed by electron cryomicroscopy

نویسندگان

  • Niklas A Hoffmann
  • Arjen J Jakobi
  • Matthias K Vorländer
  • Carsten Sachse
  • Christoph W Müller
چکیده

Electron cryomicroscopy reconstructions of elongating RNA polymerase (Pol) III at 3.9 Å resolution and of unbound Pol III (apo Pol III) in two distinct conformations at 4.6 Å and 4.7 Å resolution allow the construction of complete atomic models of Pol III and provide new functional insights into the adaption of Pol III to fulfill its specific transcription tasks.

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عنوان ژورنال:

دوره 283  شماره 

صفحات  -

تاریخ انتشار 2016